Endocrine Abstracts

Introduction: There is concern that unintended environmental exposures to numerous chemicals, including bisphenol A (BPA), triclosan (TCS) and benzophenone-3 (BP-3), all of which can be detected in serum and urine, may have adverse endocrine effects on human reproduction. Less is known about the concentrations of these chemicals in other body fluids. Here we present data, which show that these three chemicals can also be present in seminal fluid of young men.<p class="abst...

Context: Potency of the FSH-pathway varies according to polymorphisms in the promoter of the gene encoding the FSH beta subunit (FSHB −211 G>T, rs10835638) and in the gene encoding the FSH receptor (FSHR 2039 A>G, rs6166). A recent study suggested that carriers of the combination of FSHB GG and FSHR AA had the most reproductive ‘fit’ phenotype (higher serum FSH and a more sensitive FSH receptor). In pre-pubertal girls...